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Posted: Jan 15th, 2015

Merck & Co's Keytruda and Bristol-Myers Squibb's Opdivo, which work by blocking a protein calledProgrammed Death receptor (PD-1), are the first in a coming waveof immunotherapies that analysts believe could generate annualsales of more than $30 billion a year.

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The Dow Jones industrial average fell 27.74 points,or 0.16 percent, to 17,795.33, the S&P 500 lost 5.75points, or 0.28 percent, to 2,053.15 and the Nasdaq Composite dropped 20.57 points, or 0.43 percent, to 4,715.48.

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Austria's main economic research institutes slashed their2014 and 2015 growth forecasts for the export-dependent economylast month as a tepid euro zone recovery and the conflict inUkraine tensions weigh on sentiment.

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The technology giant reportedly changed its returns policy to bring the company in line with EU regulations which say customers must be able to withdraw from online purchases within 14 days without giving a reason.

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These conditions affect around 15,000 people in Ireland and symptoms can include abdominal pain, diarrhoea, fever, loss of appetite and weight loss. Left uncontrolled, symptoms may flare up, causing severe abdominal pain and frequent visits to the bathroom.

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LONDON, Dec 31 (Reuters) - Syndicated lending in Europe, theMiddle East and Africa (EMEA) reached $1.2 trillion in 2014, thehighest annual total since 2007 and 25 percent up from $930billion in 2013, according to Thomson Reuters LPC data.

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The game turned in the second quarter, when the Nets outscored Chicago, 31-14, and jumped out to an 11-point lead behind Johnson and Lopez. The Bulls never recovered. After blowing out the Nets twice this season, Chicago managed only 51 points after the first quarter. Mason Plumlee, starting at power forward, helped compensate for Lopez’s lack of rebounding, grabbing eight boards in 17 minutes. Deron Williams (six points) came off the bench for a fourth straight game and struggled offensively — missing seven of eight shots — but helped limit Chicago’s starting backcourt to just 12 points on a combined 5-for-27 shooting.

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And it is political decision-makers who send soldiers to war. This is perhaps the most difficult decision that parliamentarians have to make, as by doing so they take responsibility for the lives of the soldiers and for what these soldiers do in carrying out their task. I hope they are always aware of this. Politicians must focus on avoiding war, on the effort of talking to the others and negotiating.

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Currently in Ireland, 350 dentists work in the PDS and they see more than 250,000 children every year. They also care for some of the most vulnerable and disadvantaged members of the public, such as those with intellectual disabilities, older people and young people in the care of the HSE.

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He told Newsbeat: "There are positive signs and there is light at the end of the tunnel. The Ebola crisis, it will soon become a thing of the past for the country and once it is off our head, then the whole political social economic aspect of the country will turn around.

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Inovalon, which combines advanced cloud-based data analytics and data-driven intervention platforms to provide insights to the healthcare industry, served nearly 100 clients representing approximately 200 patient populations in 2014.

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Treasuries prices rose after the U.S. data, with benchmark10-year notes last up 16/32 in price to yield 2.1193percent, near the lowest level in two weeks. Thirty-year bonds gained 1-7/32 in price to yield 2.691 percent.


Both Redmayne and Jones were able to meet the real people they portray in the film. Redmayne first met Hawking at the scientist's Cambridge home last year, just a few days before filming began. The actor had already undertaken four months of research, which included meeting people with motor neurone disease.

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