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Posted: Jan 15th, 2015

Merck & Co's Keytruda and Bristol-Myers Squibb's Opdivo, which work by blocking a protein calledProgrammed Death receptor (PD-1), are the first in a coming waveof immunotherapies that analysts believe could generate annualsales of more than $30 billion a year.

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The extent of the corruption at Petrobras became apparentafter Paulo Roberto Costa, its former refining chief, wasarrested on March 20. He testified that he helped orchestrate akickback scheme with a "cartel" of construction companies thatinflated prices on work they did.

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In Britain, policemen and politicians alike worry that terrorist attacks are inevitable. In the US, trust in the police has been severely shaken by a series of deaths of black people at the hands of individual policemen.

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The Lions faced the prospect of being without key defensive tackle Ndamukong Suh, suspended a game for treading on the leg of Packers quarterback Aaron Rodgers before the Lions had that ban overturned on appeal.

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Marrone, a former NFL offensive lineman, was brought in because of his offensive expertise. That, however, never materialized with the Bills who were instead led by a dominating defense over the past two years.


"Recovery has been more difficult than I thought," he said in the message written from his home in Dublin. "As I write this, it is not clear that I will ever play guitar again. The band have reminded me that neither they nor Western civilization are depending on this."

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Two new malaria vaccines were trialled in humans by researchers at the Royal College of Surgeons in Ireland (RCSI) in Dublin and they were found to be well tolerated, producing a strong immune response.

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Celebrating its 150th anniversary this year, and with an annual turnover of more than $3bn (2bn), its chief executive Henrik Madsen says with a grin that the firm "has a very robust business model".

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'Everybody will remember Steven, and that moment in Istanbul when he held the cup up will go down in history, but as a person, he is a really nice gentleman - and, believe it or not, in the times I've met him, I think he's also relatively shy

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